Lung cancer Treatment's hidden toll on physical strength revealed
NCT ID NCT02493114
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study followed 150 lung cancer patients to see how their treatment—surgery, chemo, radiation, or immunotherapy—affects their physical abilities, symptoms, and quality of life. Researchers measured things like walking distance, muscle strength, and daily activity levels. The goal was to understand why patients become deconditioned and what can be done to help.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better understand how lung cancer treatments affect patients' physical abilities and daily life, leading to improved supportive care.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly improve outcomes for participants, and results may not apply to all lung cancer patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Jul 2015
- Finished
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Oct 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Consecutive patients with a primary diagnosis of non-small-cell lung cancer who will undergo treatment (surgery, chemotherapy, immunotherapy, radiotherapy, and combination of the previous ones) and score a maximal of 2 on the WHO performance status classification, will be eligible for inclusion. Healthy matched volunteers will carry out the same assessments once.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * undergoing treatment (surgery, chemotherapy, immunotherapy, radiotherapy, and combination of the previous ones) * WHO performance status of maximal 2 Exclusion Criteria: * presence of other neoplasms in the last 2 years * bone metastasis * progressive neuromuscular and neurological diseases * unstable cardiac disease * pulmonary hypertension * interstitial lung disease * orthopedic conditions that significantly impair functional status * mental or psychiatric disorders that impair the ability to comply with study procedures. * a history of cerebrovascular accident with remaining functional consequences * a history of lung cancer * difficulties in understanding and speaking Dutch
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ziekenhuis Oost-Limburg
Genk, 3600, Belgium
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