Light therapy shows promise for Hard-to-Heal diabetic foot sores
NCT ID NCT06416462
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether antimicrobial photodynamic therapy (aPDT) can improve wound healing in people with diabetic foot ulcers. Researchers compared wound quality and repair in 94 participants who received either aPDT or a placebo. The goal was to see if this light-based treatment could speed up healing and reduce wound severity.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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94 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * both sexes * chronic wounds originating from the neuropathic diabetic foot * contaminated lesions * total score obtained on the Bates-Jensen scale between 13 and 60 * who submits all requested exams Exclusion Criteria: * wounds with etiologies that are not related to the diabetic foot * ischemic diabetic foot who has an ankle-brachial index with a value between 0.7 and 1.3. * glycated hemoglobin greater than 8%.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Raquel Agnelli Mesquita-Ferrari
São Paulo, São Paulo, 11030-480, Brazil
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New wound dressing put to the test against diabetic foot ulcers
- Silver and sound: can ultrasound push nanoparticles into diabetic wounds?
- Zapping a leg nerve: can a wearable device help stubborn ulcers heal?
- Wound dressings that trap microbes: scientists test a Drug-Free approach
- Can a traditional herbal mix save limbs from diabetic ulcers?