Can a laser beam speed recovery from heart bypass surgery?
NCT ID NCT07699679
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This trial investigates whether photobiomodulation—applying low-level laser light to the surgical wound—can improve healing and reduce complications after coronary artery bypass grafting (CABG). It compares two methods of harvesting the saphenous vein (the conventional technique and the no-touch technique) in 292 heart disease patients. The study measures wound healing, functional capacity, and overall recovery. If successful, this approach could offer a simple, non-drug way to enhance postoperative outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Photobiomodulation therapy (low-level laser light)
- What this could lead to
- If effective, this light therapy could speed wound healing and reduce complications after heart bypass surgery, improving recovery.
- What could go wrong
- This is a mid-sized trial testing a device, not a drug. The effect may be small or no better than placebo, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 292 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients diagnosed with coronary artery disease scheduled to undergo elective coronary artery bypass grafting (CABG) * Use of the saphenous vein as a graft for myocardial revascularization * Ability to understand the study procedures and provide written informed consent Exclusion Criteria: * Emergency coronary artery bypass surgery * Previous surgery in the lower limb that prevents saphenous vein harvesting * Active infection at the surgical site or lower limb * Severe peripheral arterial disease in the lower limbs * Hemodynamic instability preventing study protocol procedures * Participation in another interventional clinical trial that may interfere with the outcomes of this study * Patients unable to perform postoperative functional capacity assessments * Individuals with highly pigmented skin or sensibility that may alter light absorption and penetration of the photobiomodulation therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital São Paulo, Federal University of São Paulo
São Paulo, São Paulo, 04021001, Brazil
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can AI read heart scans to predict the next heart attack?
- Can a new drug cool the hidden inflammation that fuels heart disease?
- New CT scanner aims to cut unnecessary heart procedures
- Heart bypass surgeons test which vein layout keeps grafts open
- A soft patch that watches your heart beat in real time