Acupuncture vs. herbal injections: which eases chronic neck pain better?
NCT ID NCT06520462
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared two types of needle therapy—pharmacopuncture (injecting herbal extracts) and standard acupuncture—for people with chronic neck pain lasting over three months. A total of 128 adults took part, and the main goal was to see which approach reduced pain more after five weeks. The results could help guide treatment choices for this common condition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pharmacopuncture (herbal injection) and acupuncture
- What this could lead to
- If one strategy proves more effective, it could offer a better option for managing chronic neck pain without drugs.
- What could go wrong
- This is a small, completed trial with no blinding, so results may be influenced by patient expectations. The findings may not apply to everyone with neck pain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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128 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients with neck pain persisting for more than 3 months 2. Patients with a Numeric Rating Scale (NRS) score of 5 or higher for neck pain 3. Patients aged between 19 and 70 years 4. Patients who agree to participate in the clinical study and provide a written informed consent form Exclusion Criteria: 1. Patients diagnosed with serious specific diseases that could be the cause of neck pain (e.g., spinal metastasis of tumors, acute fractures, and spinal dislocations) 2. Patients exhibiting progressive neurological deficits or severe neurological symptoms 3. Patients whose pain originates from soft tissue disorders rather than the spine (e.g., tumors, fibromyalgia, rheumatoid arthritis, gout) 4. Patients with other chronic diseases that could interfere with the interpretation of treatment effects or outcomes (e.g., stroke, myocardial infarction, kidney disease, diabetic neuropathy, dementia, epilepsy) 5. Patients currently taking steroids, immunosuppressants, psychiatric medications, or other drugs that could affect the study results 6. Patients for whom pharmacopuncture treatment is inappropriate or unsafe: those with bleeding disorders, those undergoing anticoagulant therapy, and severe diabetic patients with infection risks 7. Patients who have taken medications that could affect pain (e.g., Non-Steroidal Anti-Inflammatory Drugs, NSAIDs) or received pharmacopuncture, acupuncture, or physical therapy within the past week 8. Pregnant women, those planning to become pregnant, or those currently breastfeeding 9. Patients who have undergone cervical spine surgery within the past 3 months 10. Patients who have not completed participation in another clinical study within the past month or plan to participate in another clinical study during the study participation and follow-up period within 6 months from the date of selection 11. Patients who find it difficult to provide informed consent for participation 12. Other cases where the researcher deems participation in the clinical study to be difficult
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Bucheon Jaseng Hospital of Korean Medicine
Bucheon-si, Gyeonggi Province, 14598, South Korea
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Daejeon Jaseng Hospital of Korean Medicine
Daejeon, Daejeon, 35262, South Korea
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Dongguk University Bundang Oriental Hospital
Seongnam, GGyeonggi-do, 13601, South Korea
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Haeundae Jaseng Hospital of Korean Medicine
Busan, South Korea
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Kyung Hee University Korean Medicine Hospital
Seoul, Dongdaemun-gu, 130-701, South Korea
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Kyung Hee University Korean Medicine Hospital at Gangdong
Seoul, Gangdong-gu, 05278, South Korea
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