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Gene hunt: canagliflozin response studied in amish volunteers

NCT ID NCT02891954

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 23 times

Summary

This study gives healthy Amish volunteers a diabetes drug called canagliflozin for five days to see how their genes influence the drug's effects. Researchers measure urine sugar and other health markers to find genetic variants linked to drug response. The goal is to learn why people respond differently to SGLT2 inhibitors, not to treat any disease.

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