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Heart hole closure may boost brain power in migraine sufferers

NCT ID NCT07343154

First seen Jan 16, 2026 · Last updated May 25, 2026 · Updated 23 times

Summary

This study looks at 45 adults with migraine with aura and a small hole in the heart (PFO). It aims to see if closing the hole improves brain function, thinking, and mood. Participants will have brain scans and tests before and up to 12 months after the procedure. The goal is to understand if PFO closure can reduce migraine attacks and improve quality of life.

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