Can plugging a tiny heart hole rewire the brain and stop migraines?
NCT ID NCT07343154
Summary
This study aims to see if closing a small, common heart defect called a patent foramen ovale (PFO) can improve brain function and reduce migraine symptoms in adults. Researchers will follow 45 adults with severe migraines and a PFO, using brain scans and tests to measure changes before and after the closure procedure over one year. The goal is to understand if fixing the heart defect leads to measurable improvements in how the brain works and feels.
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