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Knee surgery showdown: partial vs. total replacement for arthritis

NCT ID NCT01326156

Disease control Sponsor: University of Aarhus Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of knee replacement surgery for people with arthritis limited to the kneecap area. One hundred patients will be randomly assigned to receive either a partial replacement (patellofemoral arthroplasty) or a full knee replacement. The goal is to see which surgery leads to better knee function, quality of life, and implant longevity over 10 years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Knee replacement surgery (patellofemoral arthroplasty or total knee replacement)
What this could lead to
If successful, this could show that a smaller surgery (PFA) works as well as a full knee replacement for certain patients, leading to faster recovery and less bone removal.
What could go wrong
This is a relatively small trial (100 people) and results may not apply to everyone. Both surgeries carry standard risks like infection, blood clots, or implant failure over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Jun 2007

Expected to finish

Oct 2040

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Isolated PF-OA Exclusion Criteria: * Medial or lateral OA

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee Patella Fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoarthritis, knee Patellofemoral knee arthroplasty

Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.