New PET/MRI scan could help kids with brain tumors get better treatment
NCT ID NCT03977896
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether a special type of brain scan (PET/MRI) can be used in children aged 5-17 with brain tumors. The scan combines two imaging techniques to give doctors more information about the tumor. Only 15 children took part, and the main goal was to see if the scan was practical and produced clear images. This is an early step toward possibly using this scan to guide treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 11C-MET (a radioactive tracer) and PET/MRI imaging
- What this could lead to
- If successful, this imaging method could help doctors identify different types of brain tumors before surgery, leading to more personalized treatment.
- What could go wrong
- This is a very small pilot study with only 15 children, so results may not apply to everyone. The scan is experimental and not yet proven to improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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15 people
The number who actually took part.
- Started
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Nov 2019
- Finished
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Nov 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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5 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients ≥ 5 years old and \< 18 years old at enrollment, * with primary posterior brain fossa tumor, metastatic or not, * hospitalized in the Department of Pediatric Neurosurgery of Femme-Mère-Enfant Hospital, and for whom a surgery is scheduled, * covered by national health insurance, * patient's parents or legal guardians who have provided written informed consent prior to participation in the study. Exclusion Criteria: * Patients with contraindication for MRI (claustrophobia, carrying metallic object) * Patients with contraindication for Gadolinium injection (including pregnancy and breastfeeding) * patient with recurring posterior brain fossa tumor * patient with brain stem infiltrative tumor
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospices Civils de Lyon - Groupement Hospitalier Est - Hôpital Femme Mère Enfant - Service de Neurochirurgie Pédiatrique
Bron, France