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New scan could sharpen cervical cancer staging

NCT ID NCT04219904

Diagnosis Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combined PET/MRI scan can more accurately show how deep cervical cancer has grown and whether it has spread to lymph nodes. About 25 people with early-stage cervical cancer that can be removed by surgery will get the scan before their operation. The goal is to see if the scan matches what doctors find during surgery, which could help guide treatment decisions in the future.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2018

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All patients with suspected clinical stage IA1-IB3 cervical cancer except patients with tumors \> 4 cm * No contraindications to MRI * Patients undergoing surgical procedure at MD Anderson * Suspected cervical cancer Exclusion Criteria: * Patients who have contraindication to MRI * Glomerular filtration rate (GFR) \< 30 * Pregnant patients * Patients with history of previous radiation * Patients with previous surgery for cervical cancer, unless residual tumor noted on physical exam * Patients with endometrial cancer extending to the cervix * Allergic reaction to gadolinium based contrast * Body weight of greater than 450 (181.4 kg) * Patients requiring general sedation * Extremely claustrophobic patients

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Conditions

The condition(s) this trial relates to.

cervical cancer cervical carcinoma Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stage IA cervical cancer Stage IA1 cervical cancer Stage IA2 cervical cancer Stage IB cervical cancer Stage IB1 cervical cancer Stage IB2 cervical cancer Stage IB3 cervical cancer

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.