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New tracer injection could sharpen cancer detection in lymph nodes

NCT ID NCT02285192

First seen Jan 04, 2026 · Last updated Jun 21, 2026 · Updated 24 times

Summary

This study tests whether injecting a radioactive sugar tracer (18F-FDG) into the cervix before a PET/CT scan can better show which pelvic lymph nodes contain cancer in women with early-stage cervical or high-grade endometrial cancer. The goal is to improve surgical planning by more accurately mapping cancer spread. The trial involves 42 women and compares imaging results with lab analysis of removed lymph nodes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (Consent only)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Consent only)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack (Consent only)

    Commack, New York, United States

  • Memorial Sloan Kettering Monmouth (Consent only)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Consent only)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester (Consent only)

    Harrison, New York, 10604, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-Fluorodeoxyglucose (18F-FDG)

What this could lead to

If successful, this could provide a more accurate way to map cancer spread to lymph nodes, helping surgeons remove the right nodes and potentially improving treatment planning.

What could go wrong

This is a small, early-phase study with only 42 participants, so results may not apply to all patients. The technique is still experimental and may not be more accurate than current methods.

Conditions

The condition(s) this trial relates to.

cervical cancer cervical carcinoma endometrial cancer endometrial carcinoma endometrium neoplasm Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.