New computer program aims to curb dangerous drinking in chronic pain patients on opioids
NCT ID NCT04592978
First seen Jun 24, 2026 · Last updated Sep 11, 2026 · Updated 2 times
Summary
This study tested a brief, computer-based personalized feedback program for adults with chronic pain who drink heavily and take prescription opioids. The program was designed to educate participants about the risks of mixing alcohol and opioids and to motivate them to reduce drinking. Over 200 participants were randomly assigned to receive either the pain-alcohol feedback or a control feedback about exercise and nutrition. The study measured changes in knowledge, motivation, and actual drinking and co-use behaviors.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Personalized feedback intervention (behavioral)
- What this could lead to
- If successful, this could point toward a brief, scalable tool to help people with chronic pain drink less and avoid dangerous alcohol-opioid combinations.
- What could go wrong
- This is an early-stage, proof-of-concept trial with 206 participants. The intervention is a single session of computer-based feedback, which may not be enough to change behavior long-term. Results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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206 people
The number who actually took part.
- Started
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Jul 2021
- Finished
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Apr 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ≥ 21 years of age * Current hazardous drinker * Current chronic pain * Current use of prescription opioid medications. Exclusion Criteria: * Current alcohol or other substance use treatment * Not being fluent in English * Current psychiatric distress or thought disorder.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Syracuse University
Syracuse, New York, 13210, United States
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