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Can a tailored diet unlock better weight loss? new study investigates

NCT ID NCT05785221

Knowledge-focused Sponsor: Chinese Academy of Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a personalized, calorie-restricted diet affects metabolism in overweight or obese Chinese adults. Researchers will measure how the body uses energy before and after a 12-week diet plan. The goal is to understand why people respond differently to the same diet and to predict who will lose the most weight.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

117 people

The number who actually took part.

Started

Mar 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 20-70 years of age, inclusive * BMI ≥ 24kg/m2 * Not in other clinical studies currently or in the past three months Exclusion Criteria: * Fasting glucose \>7.0mmol/L or diagnosed diabetes or taking insulin or other blood glucose-lowering drugs * Blood pressure \> 160/100 mmHg; diagnosed phase II or III hypertension or cannot decrease SBP under 160mmHg after anti-hypertension drugs * Fasting blood TG≥ 5.7 mmol/L or fasting LDL-C≥ 4.9 mmol/L or cannot control TG \< 5.7 mmol/L or LDL-C \< 4.9 mmol/L after taking lipid lowering drugs * Pregnant or lactating * Attempting to change body weight in the past 3 months * Use of antibiotic in the preceding 3 months for 3-serial days * Use of estrogen therapy or hormonal drugs in the preceding 6 months * Smokers * History of alcohol abuse or other substance abuse (Alcohol abuse is defined as regular alcohol consumption \> 40 g/day for females or \> 80 g/day for males) * Severe renal disease or liver disease * Severe gastrointestinal diseases * Surgical events preceding 1 year (except appendicitis or hernia surgery) * Severe cardiovascular or cerebrovascular diseases * Implantation of heart stent or any device containing metal material * Cancer or receiving radiotherapy and chemotherapy within 5 years * Hyperthyroidism or hypothyroidism * Suffering from AIDS, hepatitis A, hepatitis B and other infectious diseases * Claustrophobia * Physical disability * Any mental disorders or current use of antidepressants * Cognitive disability

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Conditions

The condition(s) this trial relates to.

nutritional disorder Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy Homeostasis Metabolism and nutrition disorder Obesity

Contacts and locations

Locations

  • Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences

    Hangzhou, Zhejiang, 310024, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.