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New study tracks wrinkle and lip changes after cosmetic filler treatment

NCT ID NCT07398768

Knowledge-focused Sponsor: Yuvell Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study is following 34 adults who are already receiving a routine perioral rejuvenation procedure using hyaluronic acid fillers. Researchers want to see how many people have at least a 1-point improvement in both lip fullness and wrinkle severity at 12 weeks. They will also measure skin roughness and volume changes at 6 and 12 weeks using specialized imaging and patient satisfaction surveys.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hyaluronic acid filler with or without lidocaine
What this could lead to
If successful, this study could provide evidence that a holistic approach to perioral rejuvenation improves lip fullness and reduces wrinkles around the mouth.
What could go wrong
This is a small, single-center observational study with no control group, so results may not apply to everyone. It only follows participants for 12 weeks, so long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 34 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients visiting the clinic for such a treatment as part of routine clinical practice.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. 18 years or older at time of treatment. 2. At least mild static perioral lines and maximum of thin lips, as assessed by the investigator. 3. Participant has a stable medical condition with no uncontrolled systemic disease. 4. Willingness to participate in the routine follow-up after 12 weeks and a signed ICF. 5. Participant already visiting the clinic for the specific treatment. Exclusion Criteria: 1. Pregnancy and breast feeding. 2. Known impairment of blood coagulation. 3. Presence of acute infection or inflammation at the proposed injection sites. 4. Hyaluronic Acid-Filler treatment in the perioral area within the last 6 months. 5. Patients with a history of autoimmune disease or who are receiving immune therapy. 6. History of hypersensitivity to hyaluronic acid, lidocaine hydrochloride or other amidetype local anaesthetics.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Crow's feet Lip aging Lip volume enhancement Perioral wrinkles

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • YUVELL

    RECRUITING

    Vienna, State of Vienna, 1010, Austria

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