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Botox study shows promise for smoothing upper face wrinkles

NCT ID NCT07374965

Symptom relief Sponsor: Yuvell Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how safe and effective a type of Botox (Letibotulinumtoxin A) is for treating wrinkles in the upper face, like frown lines, forehead lines, and crow's feet. Twenty adults under 75 with moderate to severe wrinkles received injections and were followed for 4 months. The goal was to see if the treatment improved wrinkle severity and how satisfied patients were.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

20 people

The number who actually took part.

Started

Jan 2024

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients visiting the clinic for such a treatment as part of routine clinical practice.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years or older at time of treatment. * At least mild frown lines at maximum frown, mild dynamic forehead lines at maximum eyebrow elevation or mild crow's feet at maximum smile. * Subject has a stable medical condition with no uncontrolled systemic disease. * Willingness to participate in the routine follow - up after 2 weeks and 4 months and a signed informed consent form. Exclusion Criteria: * Pregnancy and breast feeding. * Neuromuscular disease (e.g. myasthenia gravis, Eaton - Lambert syndrome). * Known impairment of blood coagulation. * Drooping eyelid. * Known allergy to botulinum toxin or human albumin (blood protein). * Presence of acute infection or inflammation at the proposed injection sites. * Botulinumtoxin treatment in the upper face within the last 16 weeks.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Canthal lines Crow's feet Forehead lines Glabellar lines

Contacts and locations

Locations

  • YUVELL

    Vienna, State of Vienna, 1010, Austria

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Other studies related to the condition(s) this trial covers.