Could a simple injection save lives after hip fracture?
NCT ID NCT06795724
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a PENG block (a numbing injection near the hip) can lower inflammation and 30-day death risk in patients over 65 having hip fracture surgery. Researchers measured blood markers of inflammation and pain levels in 60 patients. The goal is to see if this nerve block improves recovery and survival.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine (local anesthetic)
- What this could lead to
- If effective, this nerve block could reduce dangerous inflammation and improve survival after hip surgery in older adults.
- What could go wrong
- This is a small, completed study with only 60 patients. Results may not apply to all elderly patients, and the block carries rare risks like infection or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
60 people
The number who actually took part.
- Started
-
Jan 2025
- Finished
-
Aug 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
65 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ASA 1-2-3 score * Hip Fracture Surgery Exclusion Criteria: * Refusal to participate in the study * ASA score of 4 and above * Obesity (BMI \>40) * Failure of spinal block * Switching to general anesthesia * Patients undergoing revision surgery * Patients with multitrauma * Patients with old fractures (\>3 weeks) * Patients receiving preoperative and intraoperative sedation * Patients with active malignancy receiving RT, KT * Patients with active infection, patients receiving antibiotic treatment * Patients with contraindications for regional anesthesia techniques * Patients receiving chronic treatment with steroids or immunosuppressants * Patients using anti-inflammatory drugs
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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