Can magnetic pulses ease knee arthritis pain?
NCT ID NCT07443462
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether pulsed electromagnetic field (PEMF) therapy can reduce pain and improve function in people with inflammatory knee osteoarthritis. Fifty participants will receive either active PEMF or a sham treatment twice a week for 8 weeks. The study measures pain, stiffness, quality of life, and knee changes on MRI.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Pulsed Electromagnetic Field (PEMF) Therapy
- What this could lead to
- If it works, this could point toward a non-drug way to ease knee pain and improve function for people with inflammatory knee osteoarthritis.
- What could go wrong
- This is a small, early pilot study with only 50 people. It may not show clear benefits, and results might not apply to all types of knee osteoarthritis.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Knee visual analogue scale (VAS) pain of \<40 mm (0-100 mm) 2. Effusion-synovitis or Hoffa synovitis MRI semi-quantitative score of ≥2 (used to determine inflammatory subtype KOA); 3. Kellgren-Lawrence (KL) grade II and III 4. Patients can listen, speak, read, and understand Chinese; understand the pilot study's requirements and are willing to cooperate with the investigator in conducting the pilot study 5. Willing and able to provide written informed consent Exclusion Criteria: 1. Other inflammatory arthritis (e.g., gout, reactive arthritis, rheumatoid arthritis, psoriatic arthritis, and seronegative spondyloarthropathy) and systemic lupus erythematosus. 2. Participants with usual KOA interventions/ treatments 3. History of knee trauma 4. Contraindications to MRI 5. Administration of intra-articular, intramuscular, and oral glucocorticoids within the last 4 6. Pregnancy and lactation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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