Lung cancer trial: does adding chemo to immunotherapy help?
NCT ID NCT04547504
First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 28 times
Summary
This phase 3 study tests whether adding chemotherapy to the immunotherapy drug pembrolizumab works better than pembrolizumab alone for people with advanced non-small-cell lung cancer that has high levels of PDL1 (a protein that helps cancer hide from the immune system). About 349 adults who have not had prior treatment for their lung cancer will be randomly assigned to one of the two treatment groups. The main goal is to see if the combination delays cancer growth or death more effectively.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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APHP - Hôpital Cochin
Paris, 75014, France
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CH Intercommunal de Créteil
Créteil, 94010, France
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CH La Roche Sur Yon - CHD Les Oudairies
La Roche-sur-Yon, 85000, France
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CH La Réunion - Site Félix Guyon
Saint-Denis, 97400, France
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CH MEAUX
Meaux, 77108, France
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CH d'Annecy-genevois
Pringy, 74374, France
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CH de Lorient - Hôpital du Scorff
Lorient, 56100, France
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CH du Pays d'Aix
Aix-en-Provence, 13616, France
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CHRU de Brest
Brest, 29609, France
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CHU AMIENS - Hôpital Sud
Amiens, 80054, France
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CHU Bordeaux - Hôpital du Haut Levêque
Pessac, 33604, France
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CHU La Réunion - Groupe Hospitalier Sud
Saint-Pierre, 97410, France
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CHU MARSEILLE_ Hopital Nord
Marseille, 13915, France
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CHU RENNES - Hôpital Pontchailloux
Rennes, 35033, France
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CHU ROUEN - Hôpital Charles Nicolle
Rouen, 76031, France
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Centre Hospitalier Métropole Savoie
Chambéry, 73000, France
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Centre Hospitalier de Cornouaille
Quimper, 29000, France
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Centre Léon Berard
Lyon, 69008, France
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Centre de lutte contre le cancer - Centre François Baclesse
Caen, 14000, France
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Ch Villefranche Sur Saone
Villefranche-sur-Saône, 69655, France
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Chu Angers
Angers, 49033, France
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Chu Dupuytren
Limoges, 87042, France
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Hôpital Européen Marseille
Marseille, 13003, France
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Hôpital d'Instruction des Armées Toulon - Saint Anne
Toulon, 83041, France
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Institut Gustave Roussy
Villejuif, 94800, France
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Institut Paoli-Calmette
Marseille, 13000, France
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Institut de Cancérologie Strasbourg Europe
Strasbourg, 67200, France
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SAINT-PRIEST EN JAREZ - Institut de Cancérologie de la Loire
Saint-Priest-en-Jarez, 42271, France
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Saint Aubin Les Elbeuf
Saint-Aubin-lès-Elbeuf, 76503, France
Conditions
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