New hope for aggressive brain tumors: Triple-Drug attack shows promise
NCT ID NCT05463848
First seen Mar 08, 2026 · Last updated Apr 30, 2026 · Updated 10 times
Summary
This study tests a combination of three drugs (pembrolizumab, olaparib, and temozolomide) in people whose glioblastoma brain tumor has come back after prior treatment. The goal is to see if this mix can shrink the tumor or slow its growth by boosting the immune system and damaging cancer cells. About 78 adults will take part, and researchers will measure how long the cancer stays under control and how well the immune system responds.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Conditions
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