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New drug combo shows promise for Hard-to-Treat breast cancer

NCT ID NCT03393845

First seen Jan 05, 2026 · Last updated May 20, 2026 · Updated 15 times

Summary

This study tested a combination of two drugs, pembrolizumab and fulvestrant, in 47 people with advanced or metastatic hormone receptor-positive, HER2-negative breast cancer. The goal was to see if the combination could shrink tumors or keep them stable for at least four months. The approach uses immunotherapy to help the immune system fight cancer while blocking hormones that fuel tumor growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Michigan State University, Breslin Cancer Center

    Lansing, Michigan, 48910, United States

  • New York University Clinical Cancer Center

    New York, New York, 10016, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Wisconsin

    Madison, Wisconsin, 53705, United States

Conditions

Explore the condition pages connected to this study.