New drug combo shows promise for tough breast cancer

NCT ID NCT03393845

First seen Jan 05, 2026 · Last updated May 09, 2026 · Updated 14 times

Summary

This study tests whether adding the immunotherapy drug pembrolizumab to the hormone therapy fulvestrant can help control advanced breast cancer that is hormone receptor-positive and HER2-negative. About 47 adults with this type of breast cancer that has spread or cannot be removed by surgery are taking part. The goal is to see if the combination shrinks tumors or keeps the cancer stable for at least four months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Michigan State University, Breslin Cancer Center

    Lansing, Michigan, 48910, United States

  • New York University Clinical Cancer Center

    New York, New York, 10016, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Wisconsin

    Madison, Wisconsin, 53705, United States

Conditions

Explore the condition pages connected to this study.