Promising combo tackles tough cancers in early trial
NCT ID NCT03239145
First seen Mar 17, 2026 · Last updated Apr 30, 2026 · Updated 4 times
Summary
This early-phase study tested the safety of combining two drugs—pembrolizumab and AMG386—in 62 people with advanced solid tumors like melanoma, ovarian, kidney, or colorectal cancer. The goal was to find the safest dose and see if the combination could shrink tumors. While not a cure, the approach aims to better control the disease in patients who have run out of standard options.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMOR are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
-
Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
Conditions
Explore the condition pages connected to this study.