New hope for statin-intolerant patients: pemafibrate shows promise in phase 3 trial
NCT ID NCT05923281
First seen Jan 06, 2026 · Last updated May 21, 2026 · Updated 21 times
Summary
This study tested a drug called pemafibrate (K-877) in 71 adults with high cholesterol who cannot take statins because of side effects. Participants took either a low or high dose of pemafibrate or a placebo for 12 weeks. The main goal was to see if the drug lowers LDL (bad) cholesterol. This is a disease control study, not a cure, as patients would need ongoing treatment to manage their cholesterol.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Affiliated CENTRAL CLINIC of Higashiyamato Hospital
Tokyo, Japan
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Central Japan International Medical Center
Gifu, Japan
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Fukuwa Clinic
Tokyo, Japan
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Juntendo University Hospital
Tokyo, Japan
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Kohnodai Hospital, National Center for Global Health and Medicine
Chiba, Japan
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Koshigaya Municipal Hospital
Saitama, Japan
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Kumamoto University Hospital
Kumamoto, Japan
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Medical Corporation Chiseikai Tokyo Center Clinic
Tokyo, Japan
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Medical Corporation LONGWOOD Maeda Clinic
Osaka, Japan
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Mishuku Hospital
Tokyo, Japan
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NTT Medical Center Sapporo
Hokkaido, Japan
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Nakayama Clinic
Aichi, Japan
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OCROM Clinic
Osaka, Japan
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Rinku General Medical Center
Osaka, Japan
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Saitama Medical University Hospital
Saitama, Japan
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Seiwa Clinic
Tokyo, Japan
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Tashiro Endocrinology Clinic
Fukuoka, Japan
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ToCROM Clinic
Tokyo, Japan
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Tokyo Heart Summit Tokyo Heart Rhythm Hospital
Tokyo, Japan
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Tokyo-Eki Center-building Clinic
Tokyo, Japan
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Tsukuba Medical Center Foundation Tsukuba Medical Center Hospital
Ibaraki, Japan
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Yokohama Minami Kyosai Hospital
Kanagawa, Japan
Conditions
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