Pelvic floor therapy put to the test against endometriosis pain
NCT ID NCT07733583
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
Endometriosis often causes long-lasting pelvic pain that can disrupt daily life. This trial tests whether specialized pelvic floor physical therapy, combined with a structured exercise program, can lower pain more than a placebo version of the therapy. Women aged 18 to 45 with confirmed endometriosis and chronic pelvic pain will be randomly assigned to one of the two groups and followed for 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pelvic floor physical therapy and physical exercise
- What this could lead to
- If effective, this approach could offer a non-drug, non-surgical option for managing chronic pelvic pain in endometriosis.
- What could go wrong
- This is a small, early-stage trial with only 64 participants. The placebo effect is strong in pain studies, so results may not show a clear benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 64 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female, aged 18 to 45 years. * Diagnosis of endometriosis confirmed by surgery and/or imaging examinations. * Chronic pelvic pain for at least 6 months. * Visual Analog Scale (VAS) score ≥4 for chronic pelvic pain. * Willingness and ability to provide written informed consent and comply with all study procedures. Exclusion Criteria: * Current pregnancy or planned pregnancy during the study period. * Pelvic surgery within the previous 3 months. * Neuromodulation treatment within the previous 3 months. * Medical or musculoskeletal conditions that contraindicate participation in pelvic floor physical therapy or the exercise program.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital de Clínicas de Porto Alegre
RECRUITINGPorto Alegre, Rio Grande do Sul, Brazil
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Pre-Surgery pelvic floor therapy stop endometriosis pain after the operation?
- Appendix: the hidden driver of endometriosis pain?
- Allergy pill put to the test against endometriosis pain
- Can culturally adapted physiotherapy ease chronic pelvic pain?
- Can a Nerve-Pain drug quiet chronic pelvic pain?
- Can ultrasound and tissue clues reveal which endometriosis lesions carry cancer risk?