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New combo therapy shows promise for kids with Hard-to-Treat melanoma

NCT ID NCT00539591

First seen Jan 07, 2026 · Last updated Jun 14, 2026 · Updated 25 times

Summary

This study tested a combination of two drugs, temozolomide and peginterferon, in children and young adults up to age 21 with advanced or recurrent melanoma that cannot be removed by surgery. The main goal was to see how well the tumors responded to treatment and to check for side effects. The trial enrolled 29 participants and is no longer recruiting new patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Rady Children's Hospital

    San Diego, California, 92123, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • The Children's Cancer Hospital at UT M.D. Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.