New drug combo shows promise for kids with Hard-to-Treat melanoma

NCT ID NCT00539591

First seen Jan 07, 2026 · Last updated May 14, 2026 · Updated 19 times

Summary

This study tested a combination of two drugs (temozolomide and peginterferon alfa-2b) in children and young adults up to age 21 with advanced or recurrent melanoma that cannot be removed by surgery. The main goal was to see how well the tumors responded and to check for side effects. The study also looked at how long children stayed free of cancer events after treatment.

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Contacts and locations

Locations

  • Rady Children's Hospital

    San Diego, California, 92123, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • The Children's Cancer Hospital at UT M.D. Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.