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New study aims to unlock secrets of rare childhood eye disease

NCT ID NCT06273748

Knowledge-focused Sponsor: Meyer Children's Hospital IRCCS Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is tracking 290 children with non-infectious chronic uveitis, a rare eye inflammation that can cause vision loss. Researchers will collect data on symptoms, lab results, and complications over several years. The goal is to better understand the disease and identify risk factors for severe outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better understand and manage pediatric uveitis, potentially improving treatment guidelines and outcomes for children.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test new therapies. Results may take years and might not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 290 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2022

Expected to finish

May 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The data of patients who have been under the care of the hospital since 2010 will be included, and new patients diagnosed from the date of Ethical Committee approval onwards for the next 10 years will also be included

Ages

1 year to 16 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * diagnosis of non-infectious chronic uveitis before the age of 16; * signed informed consent form. Exclusion Criteria: * Patients with a diagnosis of infectious uveitis * history of malignant pathology, * history of demyelinating pathology, * history of cerebral vasculitis

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Conditions

The condition(s) this trial relates to.

uveitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Uveitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    19 sites in 5 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • - UOSD Reumatologia Pediatrica Dipartimento di Salute della Donna e del Bambino Azienda Ospedale Università di Padova

    NOT_YET_RECRUITING

    Padova, Italy

  • ATTIKON General Hospital

    RECRUITING

    Athens, 12462, Greece

  • Children's Mercy Kansas City Division of Rheumatology, Division of Rheumatology

    RECRUITING

    Kansas City, Kansas, 64108, United States

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45207, United States

  • Clinica Pediatrica, IRCCS Policlinico San Matteo

    NOT_YET_RECRUITING

    Pavia, Italy

  • Department of Medical of Health Sciences, Magna Grecia University

    RECRUITING

    Catanzaro, Italy

  • Department of Pediatric Rheumatology, Kocaeli University,

    RECRUITING

    Kocaeli, Turkey (Türkiye)

  • Department of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari

    NOT_YET_RECRUITING

    Bari, Italy

  • Dipartimento di Immunologia e Reumatologia Pediatrica, Ospedale Vito Fazzi

    RECRUITING

    Lecce, Italy

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico SC Pediatria e Immunoreumatologia PI

    RECRUITING

    Milan, Italy

  • IRCCS Ospedale Pediatrico Bambino Gesù Dipartimento Reumatologia

    NOT_YET_RECRUITING

    Roma, Italy

  • IRCCS materno infantile Burlo Garofolo

    RECRUITING

    Trieste, Italy

  • Meyer Children's Hospital IRCCS

    RECRUITING

    Florence, Firenze, Italy

  • Ospedale Spedali Civili di Brescia

    NOT_YET_RECRUITING

    Brescia, Italy

  • Santa Maria Goretti Hospital

    NOT_YET_RECRUITING

    Roma, Italy

  • The Children's Hospital Corporation d/b/a Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Unità di Immunologia e Reumatologia, Ospedale Pediatrico Regina Margherita, AOU Città della Salute e della scienza di Torino

    NOT_YET_RECRUITING

    Torino, Italy

  • Unità di Reumatologia ed Immunologia Pediatrica dell'Ospedale Fatebenefratelli Sacco di Milano

    NOT_YET_RECRUITING

    Milan, Italy

  • University fo Gent

    NOT_YET_RECRUITING

    Ghent, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.