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New drug combo aims to harness immune system against rare cancer

NCT ID NCT04303117

First seen Apr 03, 2026 · Last updated Jun 18, 2026 · Updated 13 times

Summary

This study tests two non-chemotherapy drugs, PDS01ADC and M7824, for people with advanced Kaposi sarcoma (KS) that has not responded well to prior treatment. The drugs work by helping the immune system recognize and attack tumors. About 80 adults aged 18 and older will receive the drugs alone or together for up to 96 weeks, with regular monitoring of tumor response and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

The condition(s) this trial relates to.

AIDS Kaposi's sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.