New drug PB shows promise for slowing excessive urination in kidney patients
NCT ID NCT05190744
First seen Jan 27, 2026 · Last updated May 22, 2026 · Updated 13 times
Summary
This study tested whether the drug PB can safely reduce excessive urination in people with certain kidney conditions, including inherited nephrogenic diabetes insipidus, lithium-induced diabetes insipidus, and polycystic kidney disease treated with tolvaptan. Thirty-six adults with very high urine output took PB and were monitored for changes in urine concentration and volume. The goal was to see if PB could ease the burden of frequent urination and improve quality of life.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Mayo Clinic
Jacksonville, Florida, 32224, United States
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