New weekly shot shows promise for obesity in early trial

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Chinese male or female subjects aged 18-60 years (both inclusive). 2. Body weight ≥70 kg(male) or 60 kg(female), and body mass index (BMI) ≥30.0 kg/m2 at screening. 3. Weight change \<5% in the past 3 months before screening. Exclusion Criteria: 1. Fasting Plasma Glucose（FPG） ≥7.0mmol/L or glycosylated hemoglobin (HbA1c) ≥6.5% or diagnosed diabetes 2. FPG \<3.9 mmol/L at screening and/or a history of hypoglycemia. 3. History of Cushing's syndrome, polycystic ovaries, or other hereditary endocrine disorders, or obesity caused by secondary factors such as cortisol hormones. 4. Abnormal Thyroid-Stimulating hormone(TSH), Serum Free Triiodothyronine（FT3）, Serum Free Thyroxine（FT4） or diagnosed thyroid dysfunction 5. History of multiple endocrine neoplasia syndrome type 2 (MEN-2) , medullary thyroid carcinoma (MTC) or Category 4 and above thyroid nodules by Thyroid ultrasound Chinese Ultrasound Thyroid Imaging Reporting and Data System （C-TIRADS） 6. Diagnosed cardiovascular and cerebrovascular diseases with obvious clinical significance within 6 months before screening 7. Systolic blood pressure \> 160 mmHg and/or diastolic blood pressure \> 100 mmHg at screening or randomization. 8. Time history from the starting point of P-wave to the starting point of QRS wave（PR intervals ）\> 210 msec and/or QRS complex（QRS） \> 120 msec and/or Corrected QT Interval（QTcF） \> 450 msec at screening or randomization. 9. Serum amylase or lipase \> 3× upper limit of normal (ULN) at screening or before randomization, or previously diagnosed acute/chronic pancreatitis. 10. Low density lipoprotein cholesterol(LDL-C) ≥4.40 mmol/L or triglyceride (TG) ≥5.65 mmol/L. 11. Use of any approved or unapproved drugs or products that have an effect on body weight within 3 months prior to screening 12. History of bariatric surgery for weight loss before screening.