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New combo tackles tough pancreatic cancer resistance

NCT ID NCT05518110

First seen Apr 19, 2026 · Last updated Apr 30, 2026 · Updated 3 times

Summary

This study tested whether combining two drugs, trametinib and hydroxychloroquine, could help overcome treatment resistance in people with advanced pancreatic cancer that had spread. The trial aimed to see how many patients were free of cancer growth after 12 weeks. It included 20 adults whose cancer had not responded to prior therapy, but the study was stopped early.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mater Misericordiae University Hospital

    Dublin, D07 R2WY, Ireland

  • St Vincent's University Hospital

    Dublin, DO4 T6F4, Ireland

Conditions

Explore the condition pages connected to this study.