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Can keeping a tooth fragment save your smile? new study tests Bone-Preserving trick

NCT ID NCT07171879

Disease control Sponsor: Soaad Tolba Mohammed Tolba Badawi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested methods to prevent bone and gum shrinkage after removing a front tooth. Fifty-six adults were randomly assigned to standard extraction, extraction with a blood-and-bone graft, a technique that keeps a tooth root fragment (pontic shield), or the fragment plus graft. The main goal was to see which method best preserved bone width, measured by 3D X-rays over 4 months. Results could help dentists choose the best approach for maintaining facial shape and preparing for future implants.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mineralized Plasmatic Matrix (MPM) made from patient's own blood mixed with bone particles
What this could lead to
If successful, this could offer a better way to preserve bone and gum shape after tooth extraction, improving future dental implant outcomes and appearance.
What could go wrong
This is a small, completed trial with only 56 patients, so results may not apply to everyone. The techniques are surgical and carry risks like infection or poor healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Sep 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (≥18 years). * Classified as ASA I (healthy) according to the American Society of Anesthesiologists Physical Status Classification. * Presence of Type 1 extraction sockets (intact buccal bone and soft tissues). * Adequate oral hygiene. * Sufficient inter-arch space for prosthetic rehabilitation. * Willingness to comply with study protocol and follow-up schedule. Exclusion Criteria: * Systemic conditions affecting bone metabolism or wound healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppression). * History of head and neck radiotherapy or bisphosphonate therapy. * Acute infection or suppuration at the extraction site. * Severe periodontal disease. * Root caries or tooth mobility. * Buccal bone plate loss due to vertical/horizontal root fractures or advanced periodontitis.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar ridge preservation

Contacts and locations

Locations

  • Faculty of Dentistry, Mansoura University

    Al Mansurah, Dakahlia Governorate, 35511, Egypt

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