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10,000 healthy adults tracked for decades to uncover hidden heart risks

NCT ID NCT00741728

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This long-term study is following over 10,000 healthy adults aged 50-75 to understand how the body's natural regulation of heart rate and blood pressure relates to future heart disease, stroke, and sudden death. Participants undergo non-invasive tests like a special ECG and carotid artery ultrasound. The goal is to identify early markers that could predict cardiovascular problems years in advance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help identify early warning signs for heart disease and sudden cardiac death, leading to better prevention strategies.
What could go wrong
This is an observational study, not a treatment trial. It can show links but not prove cause and effect. Results may take many years and might not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

10,157 people

The number who actually took part.

Started

May 2008

Expected to finish

Dec 2032

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult men and women affiliated to the public French Health Insurance System who benefited from a free general health check up paid by the French Health Insurance System

Ages

50 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 50-75 years, French speaking, given consent for genetic analysis, * written consent for participating in the study Exclusion Criteria: * \<50 years and \>75 years, * no French speaking, * current pregnancy, * chronic severe disease, * disagreement for genetic analysis, * step test considered as non possible or non advisable by medical decision.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Death, Sudden hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood pressure Cardiovascular disease Community based study Sudden death

Contacts and locations

Locations

  • Investigations Pré cliniques et Preventives de Paris

    Paris, 75016, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.