New combo shot may cut opioid need after chest surgery
NCT ID NCT06330168
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether adding calcitonin to a standard numbing medicine (bupivacaine) in a nerve block can better control pain after chest surgery. 92 adults having chest surgery received either the standard block or one with calcitonin added. The main goals were to see if the combo reduced morphine use in the first 24 hours and lowered the chance of long-term pain at 3 months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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92 people
The number who actually took part.
- Started
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Mar 2024
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * aged ≥ 18 years * American society of anesthesiology (ASA) physical status of I-III * scheduled for elective thoracotomy Exclusion Criteria: * Contraindication to thoracic paravertebral block as coagulopathy or local anesthetic allergy. * Pregnancy * History of cardiovascular and gastro-esophageal surgery * Preexisting pain syndrome or psychological disorders * Severe hepatic, cardiovascular, or renal disorders * Allergy to calcitonin * Patients who will be re-operated and who will report infections
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tanta University Hospitals
Tanta, Gharbia Governorate, 31527, Egypt
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Other studies related to the condition(s) this trial covers.
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