Could a simple electrical boost improve posture after knee surgery?
NCT ID NCT07741162
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This trial tests whether adding electrical stimulation to the lower back muscles, alongside standard rehabilitation, can improve spine and pelvis alignment after total knee replacement surgery. People aged 40-80 with knee osteoarthritis and measurable spinal misalignment will be randomly assigned to receive either standard rehab with quadriceps stimulation plus paraspinal stimulation, or standard rehab with quadriceps stimulation alone. The study will measure changes in spinal alignment on X-rays, as well as pain, function, and quality of life, over a 6-month period.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Paraspinal neuromuscular electrical stimulation (NMES) added to standard postoperative rehabilitation
- What this could lead to
- If it works, this could point toward a more effective rehabilitation approach after knee replacement, potentially improving posture, alignment, and overall function.
- What could go wrong
- This is a small, early-stage trial, and the added benefit of paraspinal stimulation over standard rehab alone is uncertain. Results may not apply to all patients, and electrical stimulation may cause discomfort or skin irritation.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 40 and 80 years * Diagnosis of primary knee osteoarthritis scheduled for total knee arthroplasty * Radiographic evidence of Kellgren-Lawrence grade 3-4 knee osteoarthritis * Preoperative knee flexion contracture ≥ 5° * Measurable spinopelvic malalignment, defined as meeting at least one of the following criteria: pelvic tilt (PT) \> 20°, sagittal vertical axis (SVA) \> 50 mm, or lumbar lordosis (LL) \< 40° * IIntact cognitive function based on clinical judgment, sufficient to understand and follow verbal commands, cooperate with the rehabilitation program, and reliably comply with functional assessment procedures * Provision of written informed consent * Able to stand independently and undergo standing lateral radiography Exclusion Criteria: * Prior lumbar or thoracic spinal surgery * History of hip arthroplasty * Prior knee arthroplasty (revision arthroplasty patients) * Active inflammatory arthritis (e.g., rheumatoid arthritis, psoriatic arthritis) * Neurological disease, including stroke, Parkinson's disease, peripheral neuropathy, or spinal cord pathology * Contraindications to NMES, including active cardiac pacemaker, implanted defibrillator, deep vein thrombosis, skin integrity impairment, malignancy, or epilepsy * Severe hip osteoarthritis or other lower extremity pathology significantly affecting spinopelvic alignment (e.g., leg length discrepancy, developmental hip dysplasia, contracture) * Inability to complete the standard rehabilitation protocol due to postoperative complications * Osteoporotic vertebral fracture or significant osteoporosis (T-score \< -2.5 at L1-L4) * Active treatment for malignancy * Psychiatric or medical condition that would prevent completion of the follow-up period * General contraindications to exercise
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital
Bursa, Turkey (Türkiye)
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