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New drug cocktail aims to fight tough pancreatic cancer

NCT ID NCT06313970

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 40 times

Summary

This Phase 2 trial is testing an experimental immunotherapy drug called QL1706 combined with standard chemotherapy (nab-paclitaxel and gemcitabine), with or without another drug called bevacizumab, as a first treatment for people with advanced pancreatic cancer that cannot be removed by surgery. The study will enroll 58 participants in China to see if the combination can shrink tumors and control the disease. Researchers are also monitoring safety and how long any benefits last.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

QL1706 (an experimental immunotherapy drug) plus nab-paclitaxel, gemcitabine, and optionally bevacizumab

What this could lead to

If successful, this could point toward a more effective first-line treatment for advanced pancreatic cancer, potentially shrinking tumors and extending life.

What could go wrong

This is an early Phase 2 exploratory study with only 58 participants, so results may not apply broadly. The drug combination may cause significant side effects, and there is no guarantee it will work better than current treatments.

Conditions

The condition(s) this trial relates to.

pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.