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Missing hand muscle may shield against dupuytren disease

NCT ID NCT06281509

First seen Mar 18, 2026 · Last updated Jun 22, 2026 · Updated 11 times

Summary

This study compared 243 people with and without Dupuytren disease to see if having the palmaris longus tendon (a small hand tendon not everyone has) is linked to the condition. Researchers used simple hand tests and ultrasound to check for the tendon. The goal is to understand if this tendon plays a role in developing or worsening Dupuytren disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Universitaire Ziekenhuizen KU Leuven

    Leuven, Vlaams-Brabant, 3000, Belgium

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If a link is found, this could help identify people at higher risk for Dupuytren disease based on a simple hand test.

What could go wrong

This is a small, completed observational study, not a treatment trial. It only looks for an association, so it cannot prove cause or lead directly to a therapy.

Conditions

The condition(s) this trial relates to.

palmar fibromatosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.