Can we wake and kill sleeping breast cancer cells?
NCT ID NCT04841148
First seen Apr 14, 2026 · Last updated May 22, 2026 · Updated 8 times
Summary
This study is for people with early-stage ER+ breast cancer who still have hidden cancer cells in their bone marrow after standard treatment. Researchers are testing three drug combinations—hydroxychloroquine, avelumab, and palbociclib—to see if they can clear these dormant cells and lower the risk of cancer coming back. About 96 participants will receive one of the treatments for six cycles, and the study will track safety and effectiveness.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Email: •••••@•••••
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Georgetown University
RECRUITINGWashington D.C., District of Columbia, 20007, United States
Contact Email: •••••@•••••
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Email: •••••@•••••
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
Contact Email: •••••@•••••
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Washington
RECRUITINGSeattle, Washington, 98195, United States
Contact Email: •••••@•••••
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Vanderbilt University
RECRUITINGNashville, Tennessee, 37232, United States
Contact Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.