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Scientists probe why MSA patients feel pain

NCT ID NCT01577992

Knowledge-focused Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at pain thresholds in people with multiple system atrophy (MSA) and Parkinson's disease. Researchers tested how levodopa, a common Parkinson's drug, affects pain perception. The goal is to better understand the causes of pain in MSA and improve future treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Levodopa
What this could lead to
If successful, this study could help doctors better understand and manage pain in multiple system atrophy patients.
What could go wrong
This is a small, completed observational study with only 42 participants. It does not test a new treatment, so results may not lead to direct pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Dec 2011

Finished

Nov 2013

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients from 50 to 80 years old (Male and female) * Patients suffering of a diagnosis possible or probable MSA-P with the international criteria (2008). * Patients with clinical diagnosis of Parkinson's disease according to the criteria of the UKPDSBB (Gibb et Lees, 1988; Hughes et al, 1992) * Patients with no cognitive troubles * Patients who give their informed and signed consent. * Patients affiliated to a social protection program Exclusion Criteria: * Patient suffering from an other parkinson syndrome than MSA and PD, by example progressive supranuclear palsy, corticobasal degeneration… * Patient suffering of a diagnosis possible or probable MSA-C with the international criteria * Patient suffering from another pathology causing chronic pain (rheumatic disease, traumatic or orthopedic pathologies…) * Patient under tutelage, curatella or law protection

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Conditions

The condition(s) this trial relates to.

multiple system atrophy multiple system atrophy, parkinsonian type Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple system atrophy Pain threshold

Contacts and locations

Locations

  • University Hospital, neurology

    Toulouse, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.