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New nerve block could cut opioid use after heart surgery

NCT ID NCT07420712

Symptom relief Sponsor: Kartal Kosuyolu High Speciality Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Sep 11, 2026 · Updated 2 times

Summary

This study tests whether a nerve block called the serratus posterior superior intercostal plane block can reduce pain and the need for strong painkillers after minimally invasive heart surgery. Sixty adults will be randomly assigned to receive either the nerve block plus standard pain management or standard pain management alone. Researchers will measure opioid use, pain scores, and recovery times to see if the block improves outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Bupivacaine
What this could lead to
If successful, this nerve block could become a standard way to manage pain after heart surgery, reducing the need for strong painkillers and speeding recovery.
What could go wrong
This is a small, early-stage study (60 people) testing a specific procedure. Results may not apply to all patients or surgeries, and the block may not provide significant pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

22 people

The number who actually took part.

Started

Feb 2026

Finished

Sep 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * American Society of Anesthesiologists (ASA) physical status I - III * Scheduled for elective minimally invasive coronary artery bypass surgery * Ability to understand the study procedures and provide written informed consent Exclusion Criteria: * Age under 18 years * ASA physical status other than I - III * Pregnancy * Emergency surgery * History of trauma within the previous 24 hours * Neurological disorders affecting consciousness or decision-making capacity * Psychiatric disorders affecting decision-making capacity or cooperation * Known allergy to local anesthetic agents * Infection or skin disease at the block injection site * Body mass index greater than 35 kg/m² * Body weight less than 42 kg * Coagulation disorders (international normalized ratio \>1.25, activated partial thromboplastin time \>35 seconds, or platelet count \<100,000/µL)

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Conditions

The condition(s) this trial relates to.

agnosia coronary artery disorder pain agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Analgesia

Contacts and locations

Locations

  • Kosuyolu High Specialization Training and Research Hospital

    Istanbul, 34870, Turkey (Türkiye)

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