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New combo may ease pain after gallbladder removal

NCT ID NCT06743919

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding magnesium sulfate or dexmedetomidine to a standard numbing medicine (bupivacaine) improves pain control after laparoscopic gallbladder removal. 63 adults having elective surgery received one of three mixtures in a nerve block. The goal was to see which combination provides better pain relief for the first 24 hours after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

63 people

The number who actually took part.

Started

Jan 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Patients programmed for elective LC. * American society of anesthesiologists (ASA) physical state I or II. * Age over 18 years and less than 60 years old. * Patients of both sex are included in the study. Exclusion Criteria: * •Patient refusal * Known hypersensitivity to the study drugs. * Body Mass Index \> 40 kg/m2. * Inability to accurately describe postoperative pain to investigators. * Opioid tolerance or dependence. * Preexisting history of chronic pain. * History of renal, liver, cardiac, neuropsychiatric disorder problems. * Bleeding or coagulation abnormality.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laparoscopic cholecystectomy

Contacts and locations

Locations

  • Assiut university hospitals

    Asyut, Asyut Governorate, 2067011, Egypt

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