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New study tests nerve blocks to ease severe cancer pain

NCT ID NCT07653906

Symptom relief Sponsor: Bangladesh Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Sep 04, 2026 · Updated 2 times

Summary

This study compares two types of nerve blocks—coeliac plexus block and splanchnic nerve block—to see which one reduces pain better in adults with upper abdominal cancer. Forty-four participants will receive one of the procedures and be monitored for pain, opioid use, and quality of life over three months. The goal is to find a safer, more effective way to manage severe cancer pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nerve block procedure (alcohol injection)
What this could lead to
If this works, it could offer a better way to manage severe cancer pain, reducing the need for strong painkillers and improving quality of life.
What could go wrong
This is a small, early-stage trial with only 44 participants. The results may not apply to everyone, and nerve blocks carry risks like bleeding or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 44 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patient * Both genders * Diagnosed case of upper abdominal malignancy (pancreatic, gastric, hepatic, or biliary origin) * Experiencing moderate to severe pain (≥5 on a 10 point visual analog scale) * Patients who are conscious and can communicate * No Contraindication for nerve block (e.g., coagulopathy, anticoagulant drugs) Exclusion Criteria: * Previous coeliac plexus block, splanchnic nerve block, or major abdominal nerve ablation * Severe spinal deformities or anatomical distortion at the coeliac plexus or splanchnic nerve site * Local or systemic infection at or near the block site * Known allergy to local anesthetics or neurolytic agents * Pregnancy * Lactating mother * Cognitive impairment or psychiatric illness

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Conditions

The condition(s) this trial relates to.

agnosia biliary tract cancer carcinoma of liver and intrahepatic biliary tract gastric cancer malignant pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal neoplasms Neurolytic techniques Pain management Upper abdominal malignancies

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bangladesh Medical University

    RECRUITING

    Dhaka, 1000, Bangladesh

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