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Spinal injection vs. nerve block: which eases chest surgery pain better?

NCT ID NCT07126483

Symptom relief Sponsor: Ondokuz Mayıs University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 70 adults having video-assisted chest surgery to compare two pain relief methods: a numbing injection near the spine (thoracic paravertebral block) and a small dose of morphine into the spinal fluid (intrathecal morphine). The goal was to see if the spinal morphine works as well as the nerve block in reducing the need for extra pain medicine in the first 24 hours after surgery. Participants received one of the two treatments before surgery and had their pain and recovery tracked for up to 30 days.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

70 people

The number who actually took part.

Started

Aug 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria 1. Age between 18 and 75 years 2. American Society of Anesthesiologists (ASA) physical status I-III 3. Scheduled for elective video-assisted thoracoscopic surgery (VATS) for wedge resection, segmentectomy, or lobectomy 4. Ability to understand the study protocol and provide written informed consent Exclusion Criteria 1. Refusal to participate 2. Pregnancy 3. Morbid obesity (body mass index \> 30) 4. Known allergy to opioids, local anesthetics, or NSAIDs 5. History of neuropsychiatric disorder, cognitive impairment, or inability to communicate with investigators 6. History of substance abuse 7. Current anticoagulant use or known bleeding disorder 8. Presence of systemic infection 9. Significant cardiovascular, hepatic, renal, or endocrine disease 10. History of chronic pain syndromes or chronic pain treatment 11. Emergency surgery or previous ipsilateral VATS or thoracotomy 12. Preoperative chronic opioid therapy within 3 months (≥15 mg/day for ≥30 days) 13. Severe intraoperative or postoperative bleeding, hemodynamic instability 14. Requirement for prolonged postoperative ventilation (\> 18 hours)

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intrathechal morphine Paravertebral peripheral nerve block Postoperative acute pain Video-assisted thoracoscopic surgery

Contacts and locations

Locations

  • Department of Anesthesiology, Faculty of Medicine, Ondokuz Mayis University

    Samsun, Atakum, 55139, Turkey (Türkiye)

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