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Can a skin patch before surgery ease Post-Op pain?

NCT ID NCT07733128

Symptom relief Sponsor: Clínica Dávila Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial tests whether a buprenorphine patch applied before video-assisted chest surgery can improve pain control when added to standard pain medicines. Adults scheduled for elective unilateral VATS will receive either the active patch or a placebo. Pain levels will be measured over the first week after surgery, along with the need for extra painkillers and side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a 5 mcg/hour transdermal buprenorphine patch
What this could lead to
If it works, this could offer a simple, non-invasive way to improve pain control after chest surgery and reduce the need for rescue opioids.
What could go wrong
This is a small, early-stage trial. The patch may not significantly reduce pain, and side effects like nausea or itching are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Scheduled for elective unilateral video-assisted thoracoscopic surgery (VATS). * American Society of Anesthesiologists (ASA) physical status I-III. * Able to understand the study procedures and provide written informed consent. Exclusion Criteria: * Known allergy or hypersensitivity to buprenorphine or any component of the transdermal patch. * Chronic opioid use before surgery. * Severe hepatic impairment. * Pregnancy or breastfeeding. * Inability to complete postoperative pain assessments. * Any condition that, in the investigator's opinion, could interfere with study participation or outcome assessment.

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Conditions

The condition(s) this trial relates to.

Acute Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain Thoracic surgery Video-assisted thoracoscopic surgery

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Clínica Dávila

    RECRUITING

    Santiago, Santiago Metropolitan, 8431657, Chile

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