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New study tests better pain control after lung surgery

NCT ID NCT07540104

Symptom relief Sponsor: Ondokuz Mayıs University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Aug 11, 2026 · Updated 5 times

Summary

This study compares two ways to manage pain after video-assisted lung surgery: a nerve block injected near the ribs and a small dose of morphine given into the spinal fluid. Sixty adults having elective lung surgery will be randomly assigned to one of the two methods before anesthesia. Researchers will measure how much extra pain medicine patients need in the first 24 hours, along with pain scores and recovery quality. The goal is to see which technique provides better pain relief with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine with epinephrine (nerve block) and morphine (spinal injection)
What this could lead to
If one method works better, it could offer patients a more effective way to manage pain after lung surgery with fewer opioids.
What could go wrong
This is a small, early-stage trial with only 60 people, so results may not apply to everyone. Both methods carry risks like infection or allergic reaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 75 years * American Society of Anesthesiologists physical status I to III * Scheduled for elective video-assisted thoracoscopic surgery, including wedge resection, segmentectomy, or lobectomy Exclusion Criteria: * Refusal to participate * Pregnancy * Morbid obesity (body mass index greater than 40 kg per square meter) * Allergy to study medications * Neuropsychiatric disorders, cognitive impairment, or inability to communicate * History of substance abuse * Active systemic infection or infection at the planned injection site * Severe cardiac, respiratory, hepatic, renal, or endocrine disease. * Chronic pain syndrome or ongoing chronic pain treatment * Emergency surgery or previous ipsilateral VATS or thoracotomy * Preoperative opioid use: ≥15 mg oral morphine equivalents/day for ≥30 days within the previous 3 months. * Anticipated need for postoperative mechanical ventilation. * Contraindications to neuraxial or peripheral regional anesthesia, including anticoagulant therapy, coagulopathy, infection, or relevant anatomical abnormalities.

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Conditions

The condition(s) this trial relates to.

agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain Thoracic anesthesia Video assisted thoracic surgery (VATS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ondokuz Mayis University

    RECRUITING

    Atakent, Samsun, 55270, Turkey (Türkiye)

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