New study aims to ease pain after kidney stone removal
NCT ID NCT07359391
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two nerve block techniques—dual external oblique fascial plane block and erector spinae plane block—for pain control after percutaneous nephrolithotomy (PCNL), a surgery to remove large kidney stones. Ninety adults will be randomly assigned to receive one of the blocks or standard anesthesia alone. Pain levels and medication needs will be tracked for 24 hours after surgery to see which approach works best.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- local anesthetic
- What this could lead to
- If this trial succeeds, it could identify a better nerve block technique to reduce pain and opioid use after kidney stone surgery.
- What could go wrong
- This is a small, early-stage study (90 participants) comparing two procedures. Results may not apply to all patients, and neither block may prove clearly superior.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 65 years * American Society of Anesthesiologists (ASA) physical status I or II Body mass index (BMI) between 18 and 35 kg/m² Scheduled for unilateral percutaneous nephrolithotomy (PCNL) Ability to understand the study protocol and provide written informed conse Exclusion Criteria:Refusal to participate Known allergy or hypersensitivity to local anesthetics Infection at the site of block injection Coagulopathy or bleeding disorders Chronic pain syndrome or long-term opioid use Severe hepatic, renal, or cardiac disease \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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