Saliva test reveals best pain relief for Open-Heart patients
NCT ID NCT07621744
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at two methods to reduce pain after heart surgery through a cut in the chest bone. 120 adults received either a nerve block near the breastbone, pain medicine injected into the wound, or standard painkillers. Researchers measured pain levels using a saliva test and pain scores to see which method worked best.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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120 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients scheduled for surgery through median sternotomy * Patients who provided informed consent Exclusion Criteria: * Age under 30 years * Presence of ischemic, inflammatory, or systemic disease, except cardiovascular disease * Use of analgesic medication within the last 24 hours * Diagnosis of psychiatric disorder * Presence of any oral pathology, including active dental caries, aphthous lesions, or salivary gland inflammation * Prolonged intubation or inability to be separated from mechanical ventilation for more than 8 hours
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ataturk University
Erzurum, 25240, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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