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New study tests safer pain relief after c-section to reduce opioid use

NCT ID NCT05405049

Symptom relief Sponsor: Ataturk University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two methods of pain relief after cesarean section: injecting numbing medicine into the belly and surgical wound versus giving morphine through a spinal injection. The goal was to see which approach reduces the need for extra painkillers in the first 24 hours. The trial involved 46 pregnant women undergoing planned C-sections, and researchers measured pain scores at rest and during movement.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Morphine and bupivacaine (local anesthetics)
What this could lead to
If this approach works well, it could offer a safer, effective way to manage pain after C-section without needing strong opioids.
What could go wrong
This is a small, completed trial with only 46 participants, so results may not apply to all women. Pain relief methods can vary in effectiveness from person to person.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

46 people

The number who actually took part.

Started

Jun 2022

Finished

Nov 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pregnant women * 18-50 age * ASA II * Fullterm singular pregnancy Exclusion Criteria: * Neuraxial anesthesia is contraindicated, * Allergy to the drugs to be used in the study, * Refused to participate in the study, * BMI\>35 kg/m2 * ASA≥3 * Diabetes * Preeclampsia, * Cardiovascular disease * Chronic pain and neuropathic pain, * Given opioids in the operation due to intraoperative pain, * Switched to general anesthesia, * Excessive bleeding during the operation, * Uterine atony * Drain placed in the area to be infiltrated, * History of drug addiction and psychiatric illness, * Understand Visual analog pain scale

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Conditions

The condition(s) this trial relates to.

agnosia pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Analgesia

Contacts and locations

Locations

  • Atatürk üniversty medicine school

    Erzurum, YAKUTİYE, 25100, Turkey (Türkiye)

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