New combo injection aims to ease abortion pain
NCT ID NCT07487246
First seen Apr 02, 2026 · Last updated Jun 23, 2026 · Updated 14 times
Summary
This study tests whether a paracervical block (an injection near the cervix) containing ketorolac and lidocaine can reduce pain during placement of osmotic dilators, which are used to prepare the cervix for a second-trimester abortion. About 76 participants will be randomly assigned to receive either the new combination or standard ibuprofen. The main goal is to measure pain right after the dilators are inserted.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Rush University Medical Center
Chicago, Illinois, 60612, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketorolac and lidocaine
What this could lead to
If it works, this could offer a better pain management option for people undergoing second-trimester abortion procedures.
What could go wrong
This is a small, early-phase trial with only 76 participants, so results may not apply broadly. The treatment involves a local injection, which carries risks like bleeding or infection.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.