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Which painkiller works best after shoulder surgery? new study compares options

NCT ID NCT04110665

Symptom relief Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at adding tramadol, nefopam, or opioids to standard painkillers (paracetamol and ketoprofene) for adults recovering from shoulder surgery. 92 patients were enrolled, and their recovery quality was measured using a survey. The goal was to find the best oral pain management strategy to improve recovery after same-day shoulder surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Tramadol, Nefopam, Morphine Sulfate, Oxycodone
What this could lead to
If successful, this could help doctors choose the best pain relief combination for shoulder surgery recovery.
What could go wrong
This is a small, completed Phase 4 trial with only 92 participants. Results may not apply to all patients, and opioids carry risks like dependence and side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

92 people

The number who actually took part.

Started

Sep 2017

Finished

Sep 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * shoulder surgery * under general anesthesia with an nterscalenic block * written informed consent * age \> 18 years Exclusion Criteria: * age \< 18years * emergency surgery * refusal * drug or opioid abuses

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Conditions

The condition(s) this trial relates to.

agnosia disease of the tendon Tendon Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tendon injuries

Contacts and locations

Locations

  • CHU de Nimes

    Nîmes, 30029, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.