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Nerve block may cut opioid use after back surgery

NCT ID NCT07695987

Symptom relief Sponsor: Kanuni Sultan Suleyman Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 10, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study compares two ways to control pain after a single-level lumbar microdiscectomy (a common back surgery). One group receives an ultrasound-guided nerve block (quadro-iliac plane block) with bupivacaine, while the other gets standard local infiltration of pain medicine at the surgical site. Both groups also have a patient-controlled pain pump. The main goal is to see which approach reduces total opioid use in the first 24 hours after surgery, with additional measures of pain scores, side effects, and recovery quality.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If effective, this nerve block could become a standard way to manage pain after back surgery, reducing the need for strong opioids and improving recovery.
What could go wrong
This is a small, early-stage trial (60 participants) comparing two established techniques, so the difference may be small or not statistically significant. Nerve blocks carry rare risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 75 years * American Society of Anesthesiologists physical status I to III * Scheduled for elective single-level lumbar microdiscectomy, such as L4-L5 or L5-S1 disc herniation * Planned surgery under general anesthesia * Able to provide written informed consent Exclusion Criteria: * Allergy or hypersensitivity to local anesthetics * Coagulopathy or active anticoagulant use * Infection, scar tissue, or skin lesion at the injection site * Pregnancy or breastfeeding * Chronic pain syndrome or regular opioid use * American Society of Anesthesiologists physical status IV or higher * Planned surgery for two or more levels of disc herniation

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Conditions

The condition(s) this trial relates to.

agnosia lumbar disk herniation, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain management

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital

    RECRUITING

    Istanbul, Istanbul, 34303, Turkey (Türkiye)

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